Dermatitis Herpetiformis

Dermatitis Herpetiformis is a rare and chronic skinto gluten, a protein found in wheat and other grains.
disorder characterized by extremely itchy and almostWhen gluten combines with IgA (an antibody
intolerable rashes made of bumps and blisters thatproduced by the intestines), the combination enters
normally occur on the elbows, knees, shoulders, back,the blood stream and begins circulating. This
and buttocks. It is believed to be related to coeliaccombination then causes small blood vessels in the
disease, a disorder of the small intestine. Dermatitisskin to get clogged up, attracts while blood cells, and
Herpetiformis is also referred to as Durhing's disease.secretes chemicals which then cause rashes to form.
The predominant symptoms of Dermatitis
Herpetiformis include intense burning, stinging, andTreatment
itching sensations in affected areas. Diagnosis isThe most effective means of treating Dermatitis
mainly through physical evidence and analysis of skinHerpetiformis is with a drug called Dapsone. Dapsone
biopsies. The ailment most commonly affects youngcan alleviate symptoms within days but it does have
adults, particularly males, aged 20 and higher.side effects like haemolytic anaemia, a blood disorder.
Estimates suggest that the disease currently affectsTherefore, its usage should be monitored closely and
about 11.2 out of every 100,000 people in the Unitedit should only be taken under the supervision of a
States and about 10 out of every 100,000 peoplequalified physician. For those intolerant or allergic to
internationally. The disease is more common in youngDapsone, topical and systemic steroids and
males of European descent (particularly fromSulfapyridine are also available options. A gluten free
Scandinavian countries) than those of other ethnicdiet is also highly recommended and this reduces
backgrounds.dependence on Dapsone and the risk of developing
The exact cause of Dermatitis Herpetiformis isother conditions.
unknown but it is believed to be related to an allergy